Growth kinetics of cell subsets and clonogenic progenitors
| Component . | Mean Expansion* . | ||||
|---|---|---|---|---|---|
| Day 1 . | Day 2 . | Day 3 . | Day 4 . | Day 6 . | |
| Total cells | 1.1 (n = 2) | 1.2 (n = 4) | 3.8 (n = 2) | 4.2 (n = 20) | 12.6 (n = 1) |
| CD34+ cells | 1.0 (n = 2) | 1.2 (n = 4) | 4.0 (n = 2) | 4.9 (n = 20) | 19.3 (n = 1) |
| CD34+CD38− cells | 2.3 (n = 2) | 6.4 (n = 4) | 46.5 (n = 2) | 166.1 (n = 20) | 127.1 (n = 1) |
| CFC | ND | 1.4 (n = 2) | ND | 5.0 (n = 13) | 9.4 (n = 1) |
| CAFC | ND | 1.0 (n = 2) | ND | 3.6 (n = 2) | ND |
| Component . | Mean Expansion* . | ||||
|---|---|---|---|---|---|
| Day 1 . | Day 2 . | Day 3 . | Day 4 . | Day 6 . | |
| Total cells | 1.1 (n = 2) | 1.2 (n = 4) | 3.8 (n = 2) | 4.2 (n = 20) | 12.6 (n = 1) |
| CD34+ cells | 1.0 (n = 2) | 1.2 (n = 4) | 4.0 (n = 2) | 4.9 (n = 20) | 19.3 (n = 1) |
| CD34+CD38− cells | 2.3 (n = 2) | 6.4 (n = 4) | 46.5 (n = 2) | 166.1 (n = 20) | 127.1 (n = 1) |
| CFC | ND | 1.4 (n = 2) | ND | 5.0 (n = 13) | 9.4 (n = 1) |
| CAFC | ND | 1.0 (n = 2) | ND | 3.6 (n = 2) | ND |
Expansion is expressed as the fold increase in number relative to preculture (day 0) levels. ND indicates not done.