Table 3. Therapy and clinical outcome of... | American Society of Hematology

Table 3.

Therapy and clinical outcome of 18 V-form APL patients on Intergroup protocol 0129

UPN	Induction Therapy	CR	Maintenance Arm	Relapse	CR Duration (Months)	Status	Survival (Months)
C132	DA	No	—	—	—	Dead	19
C205	DA	Yes^3-150	ATRA	—	—	Alive	51
S448	DA	Yes	Obs	Yes	8	Dead	27
S444	ATRA	Yes	ATRA	No	40	Alive	42
E076	ATRA	No	—	—	—	Dead	35
C902	ATRA	Yes	Obs	No	46	Alive	48
E003	ATRA^3-151	No	—	—	—	Dead	27
E011	DA	Yes	ATRA	Yes	8	Dead	11
E801	DA	Yes	ATRA	No	48	Alive	49
E036	DA	Yes	—	No	1^3-152	Alive	67
E086	DA^3-153	Yes	Obs	Yes	16	Alive	52
S386	DA	Yes	Obs	Yes	28	Dead	35
E805	DA	No	—	—	—	Dead	14
C179	ATRA	Yes	—^3-6	Yes	48	Alive	60
E027	DA	No	—	—	—	Dead	3
E091	DA	Yes	Obs	No	50	Alive	51
C183	ATRA	Yes	ATRA	No	5	Alive	7
E070	ATRA	Yes	Obs	Yes	10	Dead	13

UPN	Induction Therapy	CR	Maintenance Arm	Relapse	CR Duration (Months)	Status	Survival (Months)
C132	DA	No	—	—	—	Dead	19
C205	DA	Yes^3-150	ATRA	—	—	Alive	51
S448	DA	Yes	Obs	Yes	8	Dead	27
S444	ATRA	Yes	ATRA	No	40	Alive	42
E076	ATRA	No	—	—	—	Dead	35
C902	ATRA	Yes	Obs	No	46	Alive	48
E003	ATRA^3-151	No	—	—	—	Dead	27
E011	DA	Yes	ATRA	Yes	8	Dead	11
E801	DA	Yes	ATRA	No	48	Alive	49
E036	DA	Yes	—	No	1^3-152	Alive	67
E086	DA^3-153	Yes	Obs	Yes	16	Alive	52
S386	DA	Yes	Obs	Yes	28	Dead	35
E805	DA	No	—	—	—	Dead	14
C179	ATRA	Yes	—^3-6	Yes	48	Alive	60
E027	DA	No	—	—	—	Dead	3
E091	DA	Yes	Obs	No	50	Alive	51
C183	ATRA	Yes	ATRA	No	5	Alive	7
E070	ATRA	Yes	Obs	Yes	10	Dead	13

UPN indicates unique patient number; CR, complete remission; DA, daunorubicin and Ara-C; ATRA, all-trans retinoic acid; Obs, observation.

F3-150

Because the CR for case C205 was undocumented, no CR duration is available, and this case is not included in the disease-free survival plot shown in Figure 3.

F3-151

No CR after ATRA for 42 days; crossed over to DA and achieved CR.

F3-152

Taken off protocol and received alternative consolidation. Censored at day 28 for CR duration.

F3-153

Randomized to ATRA but received DA instead due to refractory leukocytosis.

F3-6

Not registered to the maintenance arm.

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