Table 4.

Negative regulatory mechanisms of the Jak-Stat pathway

Mechanism Refs
Receptor-mediated endocytosis  82, 83 
Dominant-negative Stats  84, 85  
PIAS family of proteins 72, 86  
CIS/SOCS/SSI family of proteins  88, 89  
Tyrosine phosphatases  114, 115 
Mechanism Refs
Receptor-mediated endocytosis  82, 83 
Dominant-negative Stats  84, 85  
PIAS family of proteins 72, 86  
CIS/SOCS/SSI family of proteins  88, 89  
Tyrosine phosphatases  114, 115 
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