Epitope Models (9 and 37) With the Reaction Pattern of the New Partial D Tested With MoAbs Described in the Nantes Workshop (1996)
| Epitope Model . | Nantes . | DAR . | |
|---|---|---|---|
| 1-9 . | 1-37 . | ||
| 1 | 1 | LHM169/81 | ± |
| 1 | 2 | LHM70/45, LHM174/102 | − |
| 2 | 3 | LOR12-E2, LORE | ± |
| 2 | 4 | LOR28-7E6 | − |
| 3 | 5 | LOR11-2D9, LHM76/55, H41.11B7, H41 | + |
| 4 | 6 | LOR17-6C7 | + |
| 5 | 7 | CAZ7-4C5 | − |
| HIRO-6 | ± | ||
| 5 | 10 | AUB-2F7/Fiss, MAR-1F8 | − |
| C205-29, CLAS1-126, BS229, BS231 | ± | ||
| 5 | 11 | 819 | − |
| 6/7 | 12 | 175-2, LOR17-8D3, P3AF6, RUM-1, MS201, P3x61 | ± |
| 6/7 | 13 | D-89/47, 17010C9, LOR28-21D3, H2D5D2F5 | ± |
| F5S | + | ||
| 6/7 | 15 | D-90/7, D-90/17, NOI, SAL20-12D5, LHM50/2B, LHM169/80, BIRMA-DG3, BIRMA-D56, L87.1G7, D10 | ± |
| 6/7 | 17 | HeM-92, NaTH53-2A7, P3F17, HIRO-I, HS114 | − |
| B9A4B2, NaTH28-3C11, BS232 | ± | ||
| 6/7 | 18 | LHM59/20, T3D2F7, P3F20 | − |
| HG/92, LHM50/3.5, LHM59/25, HM10 | ± | ||
| ID6-H8 | + | ||
| 6/7 | 21 | VOL-3F6 | − |
| D-90/12, BRAD5 | ± | ||
| HIRO-2 | + | ||
| 8 | 22 | LHM59/19 | − |
| 9 | 23 | P3x21223B10 | − |
| BIRMA-D6, P3G6, MS26, HIRO-4, HIRO-7, HIRO-8 | ± | ||
| 31 | NOU | − | |
| 32 | ZIG-189 | − | |
| 33 | NaTH87-4A5 | − | |
| 34 | LORA | − | |
| 35 | SALSA-12 | − | |
| 36 | NAU3-2E8, BTSN6, LHM76/59 | ± | |
| NAU6-4D5 | + | ||
| 37 | 822, HIRO-3 | + | |
| Epitope Model . | Nantes . | DAR . | |
|---|---|---|---|
| 1-9 . | 1-37 . | ||
| 1 | 1 | LHM169/81 | ± |
| 1 | 2 | LHM70/45, LHM174/102 | − |
| 2 | 3 | LOR12-E2, LORE | ± |
| 2 | 4 | LOR28-7E6 | − |
| 3 | 5 | LOR11-2D9, LHM76/55, H41.11B7, H41 | + |
| 4 | 6 | LOR17-6C7 | + |
| 5 | 7 | CAZ7-4C5 | − |
| HIRO-6 | ± | ||
| 5 | 10 | AUB-2F7/Fiss, MAR-1F8 | − |
| C205-29, CLAS1-126, BS229, BS231 | ± | ||
| 5 | 11 | 819 | − |
| 6/7 | 12 | 175-2, LOR17-8D3, P3AF6, RUM-1, MS201, P3x61 | ± |
| 6/7 | 13 | D-89/47, 17010C9, LOR28-21D3, H2D5D2F5 | ± |
| F5S | + | ||
| 6/7 | 15 | D-90/7, D-90/17, NOI, SAL20-12D5, LHM50/2B, LHM169/80, BIRMA-DG3, BIRMA-D56, L87.1G7, D10 | ± |
| 6/7 | 17 | HeM-92, NaTH53-2A7, P3F17, HIRO-I, HS114 | − |
| B9A4B2, NaTH28-3C11, BS232 | ± | ||
| 6/7 | 18 | LHM59/20, T3D2F7, P3F20 | − |
| HG/92, LHM50/3.5, LHM59/25, HM10 | ± | ||
| ID6-H8 | + | ||
| 6/7 | 21 | VOL-3F6 | − |
| D-90/12, BRAD5 | ± | ||
| HIRO-2 | + | ||
| 8 | 22 | LHM59/19 | − |
| 9 | 23 | P3x21223B10 | − |
| BIRMA-D6, P3G6, MS26, HIRO-4, HIRO-7, HIRO-8 | ± | ||
| 31 | NOU | − | |
| 32 | ZIG-189 | − | |
| 33 | NaTH87-4A5 | − | |
| 34 | LORA | − | |
| 35 | SALSA-12 | − | |
| 36 | NAU3-2E8, BTSN6, LHM76/59 | ± | |
| NAU6-4D5 | + | ||
| 37 | 822, HIRO-3 | + | |
The serology was performed as described before.24 This pattern was found in all 9 individuals expressing DAR homozygously or next to a D-negative allele. These results were confirmed by Joyce Poole's laboratory of the IBGRL.
Abbreviations: −, negative MoAb reaction; ±, positive MoAb reaction, but weaker than that of normal Rh (D)-positive control cells; +, positive MoAb reaction.