Total variances of the self-reactive antibody repertoires of IgM of patients with WAIHA and healthy blood donors
Tissue Extract . | Total Variance of Repertoires of Reactivity of IgM . | |
---|---|---|
Patients With WAIHA . | Healthy Blood Donors . | |
Kidney | 323.8 | 367.2 |
Liver | 265.0 | 246.6 |
Stomach | 440.8 | 206.5 |
RBC extracts | 51.4 | 84.6 |
RBC membranes | 460.0 | 240.0 |
Tissue Extract . | Total Variance of Repertoires of Reactivity of IgM . | |
---|---|---|
Patients With WAIHA . | Healthy Blood Donors . | |
Kidney | 323.8 | 367.2 |
Liver | 265.0 | 246.6 |
Stomach | 440.8 | 206.5 |
RBC extracts | 51.4 | 84.6 |
RBC membranes | 460.0 | 240.0 |
Total variances of repertoires of antibody reactivities of IgM in whole plasma with self-antigens in extracts of kidney, liver, stomach, RBCs, and in RBC membranes were calculated separately in a 40- to 60-dimension vector space, depending on the tissue extract. None of the differences between total variances were significant as assessed by the F test.