Table 2.

Major manifestations of the retinoic acid syndrome

Manifestation % of Patients
Respiratory distress  84  
Fever  81  
Pulmonary edema  54  
Pulmonary infiltrates  52  
Pleural/pericardial effusion  36  
Hypotension  18  
Bone pain  14 
Headache  14  
Congestive heart failure  11  
Acute renal failure  11 
Manifestation % of Patients
Respiratory distress  84  
Fever  81  
Pulmonary edema  54  
Pulmonary infiltrates  52  
Pleural/pericardial effusion  36  
Hypotension  18  
Bone pain  14 
Headache  14  
Congestive heart failure  11  
Acute renal failure  11 
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