Table 4.

Genotype Distribution of SH-FcγRIIIb in Individuals in Whom a PCR Fragment Could Be Amplified With NA2-Specific Primers

AA (n = 123) CA (n = 157)
SH(−) 80 (65%)  149 (95%)  
SH(+)  43 (35%)  8 (5%)  
 P < .0001  
AA (n = 123) CA (n = 157)
SH(−) 80 (65%)  149 (95%)  
SH(+)  43 (35%)  8 (5%)  
 P < .0001  

Individuals in this analysis were restricted to those in whom a PCR fragment was amplified with NA2-specific primers (84% of AA and 90% of CA). SfaN1 digestion of amplicon generated with NA2-specific oligonucleotide primers was analyzed by agarose gel; digestion by SfaN1 indicates the presence of the SH-FcγRIIIb sequence. The difference between the 2 groups was significant at P < .0001.

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