Genotype Distribution of SH-FcγRIIIb in Individuals in Whom a PCR Fragment Could Be Amplified With NA2-Specific Primers
. | AA (n = 123) . | CA (n = 157) . |
---|---|---|
SH(−) | 80 (65%) | 149 (95%) |
SH(+) | 43 (35%) | 8 (5%) |
P < .0001 |
. | AA (n = 123) . | CA (n = 157) . |
---|---|---|
SH(−) | 80 (65%) | 149 (95%) |
SH(+) | 43 (35%) | 8 (5%) |
P < .0001 |
Individuals in this analysis were restricted to those in whom a PCR fragment was amplified with NA2-specific primers (84% of AA and 90% of CA). SfaN1 digestion of amplicon generated with NA2-specific oligonucleotide primers was analyzed by agarose gel; digestion by SfaN1 indicates the presence of the SH-FcγRIIIb sequence. The difference between the 2 groups was significant at P < .0001.