Concentrations of Antifolates Tested in the In Situ TS Inhibition Assay
| Antifolate . | Short Incubation (μmol/L) . | Continuous Incubation (μmol/L) . |
|---|---|---|
| MTX | 0.156-40 | 0.0039-1 |
| TMQ | 0.08-50 | 0.0016-1 |
| GW1843U89 | 0.001-0.63 | 0.00025-0.064 |
| MTA | 0.039-10 | 0.039-10 |
| Raltitrexed | 0.0013-0.32 | 0.00063-0.16 |
| ZD9331 | 0.04-25 | 0.0016-0.4 |
| Antifolate . | Short Incubation (μmol/L) . | Continuous Incubation (μmol/L) . |
|---|---|---|
| MTX | 0.156-40 | 0.0039-1 |
| TMQ | 0.08-50 | 0.0016-1 |
| GW1843U89 | 0.001-0.63 | 0.00025-0.064 |
| MTA | 0.039-10 | 0.039-10 |
| Raltitrexed | 0.0013-0.32 | 0.00063-0.16 |
| ZD9331 | 0.04-25 | 0.0016-0.4 |