Sequential Data on One Patient Before and After Starting Regular Blood Transfusions
| . | Untransfused (age 2.8 years) . | Regularly Transfused (age 6 years) . | Predicted (untransfused, age 6 years) . |
|---|---|---|---|
| α/non-α | 2.6 | 2.9 | 2.6 |
| α/γ | 8.9 | 29 | 9.6 |
| α/βE | 3.7 | 3.4 | 3.8 |
| βE/γ | 2.4 | 8.3 | 2.6 |
| HbE/HbF | 2.0 | 5.1 | — |
| . | Untransfused (age 2.8 years) . | Regularly Transfused (age 6 years) . | Predicted (untransfused, age 6 years) . |
|---|---|---|---|
| α/non-α | 2.6 | 2.9 | 2.6 |
| α/γ | 8.9 | 29 | 9.6 |
| α/βE | 3.7 | 3.4 | 3.8 |
| βE/γ | 2.4 | 8.3 | 2.6 |
| HbE/HbF | 2.0 | 5.1 | — |
The predicted values arise from regression analysis on the ratios of the 13 untransfused patients aged ≤10 years, based on the equations [α/non-α = 2.2 + (0.05 × age), R = 0.36], [α/γ = 5.1 + (0.72 × age), R = 0.55], [α/βE = 4.2 − (0.75 × age),R = 0.35], and [βE/γ = 1.1 + (0.25 × age),R = 0.63].