Erythrocyte Enzyme Levels of Patient N.S.
| Enzyme or Intermediate Level . | Normal Range . | Patient . | Mother . | Brother . |
|---|---|---|---|---|
| Hexokinase | 0.67 to 1.79 | 3.26 | ||
| Glucose phosphate isomerase | 25.45 to 51.60 | 40.50 | ||
| Phosphofructokinase (PFK) | 3.02 to 6.38 | 2.18 | ||
| Aldolase | 1.01 to 3.29 | 6.10 | ||
| Triose phosphate isomerase | 805 to 1971 | 1463 | ||
| Glyceraldehyde phosphate dehydrogenase | 119.5 to 258.4 | 190.6 | ||
| Diphosphoglycerate mutase | 1.21 to 5.27 | 5.29 | ||
| Phosphoglycerate kinase | 175.9 to 260.6 | 223.4 | ||
| Monophosphoglycerate mutase | 13.40 to 24.10 | 32.56 | ||
| Enolase | 2.91 to 6.00 | 5.49 | ||
| Pyruvate kinase (PK) | 7.32 to 16.0 | 22.7 | ||
| Lactate dehydrogenase | 60.4 to 214.0 | 170.9 | ||
| Glucose-6-phosphate dehydrogenase | 9.3 to 14.2 | 21.8 | ||
| 6-Phosphogluconate dehydrogenase | 6.75 to 10.70 | 15.85 | ||
| Glutathione reductase | 6.62 to 8.83 | 7.62 | ||
| Glutathione peroxidase | 21.40 to 40.30 | 25.77 | ||
| GOT | 2.19 to 5.20 | 15.71 | ||
| Adenylate kinase | 87.7 to 241.0 | 192.0 | ||
| GST | 1.45 to 4.15 | 0.83 | ||
| Pyrimidine 5′ nucleotidase (mU/g Hb) | 100.5 to 176.1 | 262.7 | ||
| Adenosine deaminase | 0.70 to 1.60 | 0.92 | ||
| GSH | 4.50 to 8.70 | 0.21 | 5.14 | 5.31 |
| γ-Glutamylcysteine synthetase | 0.88 to 1.98 | 0.14 | 0.42 | 0.70 |
| Glutathione synthetase | 0.24 to 0.53 | 0.40 |
| Enzyme or Intermediate Level . | Normal Range . | Patient . | Mother . | Brother . |
|---|---|---|---|---|
| Hexokinase | 0.67 to 1.79 | 3.26 | ||
| Glucose phosphate isomerase | 25.45 to 51.60 | 40.50 | ||
| Phosphofructokinase (PFK) | 3.02 to 6.38 | 2.18 | ||
| Aldolase | 1.01 to 3.29 | 6.10 | ||
| Triose phosphate isomerase | 805 to 1971 | 1463 | ||
| Glyceraldehyde phosphate dehydrogenase | 119.5 to 258.4 | 190.6 | ||
| Diphosphoglycerate mutase | 1.21 to 5.27 | 5.29 | ||
| Phosphoglycerate kinase | 175.9 to 260.6 | 223.4 | ||
| Monophosphoglycerate mutase | 13.40 to 24.10 | 32.56 | ||
| Enolase | 2.91 to 6.00 | 5.49 | ||
| Pyruvate kinase (PK) | 7.32 to 16.0 | 22.7 | ||
| Lactate dehydrogenase | 60.4 to 214.0 | 170.9 | ||
| Glucose-6-phosphate dehydrogenase | 9.3 to 14.2 | 21.8 | ||
| 6-Phosphogluconate dehydrogenase | 6.75 to 10.70 | 15.85 | ||
| Glutathione reductase | 6.62 to 8.83 | 7.62 | ||
| Glutathione peroxidase | 21.40 to 40.30 | 25.77 | ||
| GOT | 2.19 to 5.20 | 15.71 | ||
| Adenylate kinase | 87.7 to 241.0 | 192.0 | ||
| GST | 1.45 to 4.15 | 0.83 | ||
| Pyrimidine 5′ nucleotidase (mU/g Hb) | 100.5 to 176.1 | 262.7 | ||
| Adenosine deaminase | 0.70 to 1.60 | 0.92 | ||
| GSH | 4.50 to 8.70 | 0.21 | 5.14 | 5.31 |
| γ-Glutamylcysteine synthetase | 0.88 to 1.98 | 0.14 | 0.42 | 0.70 |
| Glutathione synthetase | 0.24 to 0.53 | 0.40 |
Activity of enzymes is presented as international units per gram of Hb. GSH levels are millimoles per liter.