Number of Splenic T Cells, B Cells, and NK Cells in Wild-Type and Reconstituted γc KO Mice
| Mice . | BMT . | CD3+B220− (T cells) . | CD3−B220+ (B cells) . | TCRβ−NK1.1+ (NK cells) . |
|---|---|---|---|---|
| Wild-type (n = 4) | — | 25.9 ± 1.1 | 54.2 ± 2.7 | 2.1 ± 0.22 |
| γcKO (n = 6)* | — | 7.8 ± 2.5 | 0.6 ± 0.1 | 0.04 ± 0.01 |
| γcKO (n = 4) | Wild-type BM | 13.5 ± 3.8 | 40.7 ± 9.6 | 1.17 ± 0.35 |
| γcKO (n = 8) | hγc-transduced γcKO BM | 14.6 ± 2.8 | 45.5 ± 12.7 | 0.62 ± 0.1 |
| γcKO (n = 4) | Mock-transduced γcKO BM | 1.1 ± 0.2 | 0.1 ± 0.1 | 0.03 ± 0.02 |
| Mice . | BMT . | CD3+B220− (T cells) . | CD3−B220+ (B cells) . | TCRβ−NK1.1+ (NK cells) . |
|---|---|---|---|---|
| Wild-type (n = 4) | — | 25.9 ± 1.1 | 54.2 ± 2.7 | 2.1 ± 0.22 |
| γcKO (n = 6)* | — | 7.8 ± 2.5 | 0.6 ± 0.1 | 0.04 ± 0.01 |
| γcKO (n = 4) | Wild-type BM | 13.5 ± 3.8 | 40.7 ± 9.6 | 1.17 ± 0.35 |
| γcKO (n = 8) | hγc-transduced γcKO BM | 14.6 ± 2.8 | 45.5 ± 12.7 | 0.62 ± 0.1 |
| γcKO (n = 4) | Mock-transduced γcKO BM | 1.1 ± 0.2 | 0.1 ± 0.1 | 0.03 ± 0.02 |
Values are presented as mean number of cells × 10−6 ± SEM.
Abbreviations: BM, bone marrow; BMT, bone marrow transplantation.
n = 5 for NK cell numbers.