Table 4. Clinical Parameters of the... | American Society of Hematology

Table 4.

Clinical Parameters of the International Index and Chromosomal Abnormalities as Risk Factors for Survival in 68 Patients With cb and 28 Patients With B-ib Lymphoma (Multivariate Analyses)

	cb Lymphomas		ib Lymphomas
	P Value	Risk Ratio	P Value	Risk Ratio
Clinical Risk Factor
Age >60 yr	.37	1.47	0.81	1.14
Clinical Stage (Ann Arbor Stage III or IV)	.61	0.80	0.76	0.83
Serum LDH >240 U/l	.19	1.79	0.36	1.88
Karnofsky Index ≤70%	.01	0.25	0.03	0.12
No. of E-sites^4-150 ≥2	.32	0.53	0.60	0.65

Clinical Risk Factor or Chromosomal Abnormality
Age >60 yr	.018	1.05	—	—
Clinical Stage (Ann Arbor Stage III or IV)	.035	2.44	—	—
dup(1)(q)	.065	2.27	—	—
del(1)(q)	.084	2.39	—	—
+5	.089	0.17	—	—
der(15)(q)	.125	0.19	—	—
Karnofsky Index ≥70%	—	—	.001	0.01
der(8)(q)	—	—	.003	13.20
der(7)(q)	—	—	.009	6.91

	cb Lymphomas		ib Lymphomas
	P Value	Risk Ratio	P Value	Risk Ratio
Clinical Risk Factor
Age >60 yr	.37	1.47	0.81	1.14
Clinical Stage (Ann Arbor Stage III or IV)	.61	0.80	0.76	0.83
Serum LDH >240 U/l	.19	1.79	0.36	1.88
Karnofsky Index ≤70%	.01	0.25	0.03	0.12
No. of E-sites^4-150 ≥2	.32	0.53	0.60	0.65

Clinical Risk Factor or Chromosomal Abnormality
Age >60 yr	.018	1.05	—	—
Clinical Stage (Ann Arbor Stage III or IV)	.035	2.44	—	—
dup(1)(q)	.065	2.27	—	—
del(1)(q)	.084	2.39	—	—
+5	.089	0.17	—	—
der(15)(q)	.125	0.19	—	—
Karnofsky Index ≥70%	—	—	.001	0.01
der(8)(q)	—	—	.003	13.20
der(7)(q)	—	—	.009	6.91

E-sites, extranodal manifestation.