Output of Different Types of CFC in LTC From LTC-IC Changes According to the Ontological Origin of the LTC-IC
| CFC Analyzed . | No. of CFC Per LTC-IC . | % of Total CFC Per LTC-IC . | ||||
|---|---|---|---|---|---|---|
| Fetal Liver . | Cord Blood . | Adult Marrow . | Fetal Liver . | Cord Blood . | Adult Marrow . | |
| CFU-E + BFU-E | 14 ± 7 | 0.6 ± 0.4 | 0.2 ± 0.1 | 17 ± 7 | 2 ± 2 | 1 ± 1 |
| CFU-GM | 57 ± 14 | 28 ± 1 | 18 ± 3 | 81 ± 9 | 98 ± 2 | 99 ± 1 |
| CFU-GEMM | 3 ± 1 | 0.03 ± 0.03 | 0.003 ± 0.003 | 2 ± 1 | 0.09 ± 0.09 | 0.03 ± 0.03 |
| Total | 72 ± 18 | 28 ± 1 | 18 ± 2 | 100 | 100 | 100 |
| CFC Analyzed . | No. of CFC Per LTC-IC . | % of Total CFC Per LTC-IC . | ||||
|---|---|---|---|---|---|---|
| Fetal Liver . | Cord Blood . | Adult Marrow . | Fetal Liver . | Cord Blood . | Adult Marrow . | |
| CFU-E + BFU-E | 14 ± 7 | 0.6 ± 0.4 | 0.2 ± 0.1 | 17 ± 7 | 2 ± 2 | 1 ± 1 |
| CFU-GM | 57 ± 14 | 28 ± 1 | 18 ± 3 | 81 ± 9 | 98 ± 2 | 99 ± 1 |
| CFU-GEMM | 3 ± 1 | 0.03 ± 0.03 | 0.003 ± 0.003 | 2 ± 1 | 0.09 ± 0.09 | 0.03 ± 0.03 |
| Total | 72 ± 18 | 28 ± 1 | 18 ± 2 | 100 | 100 | 100 |
Values for fetal liver LTC-IC were derived from limiting dilution experiments described in the text. In each experiment, the total number of CFC (of the type indicated) produced in all of the cultures was divided by the total number of LTC-IC placed into these cultures. Values for cord blood and adult marrow LTC-IC were similarly calculated from the limiting dilution experiments reported in Hogge et al.43