Table 1.

Mpl Isoform Expression Pattern in PV Patients

Patient No. Mpl Isoform Pattern SplenomegalyTime From Diagnosis
 A  
1   0  0.5  
 0  0.6  
3   0  1  
4   0  1  
 0  1.5  
 A = B  
6   1  1  
7   3  
8   1  3  
9   0  4  
10   4  
11   0  5  
12   0  6  
 B > A 
13   0  5  
14   1  5  
15   2  10 
16   2  17  
17   0  17  
 B  
18  2  6  
19   2  7  
20   2  10  
21  2  10  
22   2  18  
23   2  18  
24  0* 17 
Patient No. Mpl Isoform Pattern SplenomegalyTime From Diagnosis
 A  
1   0  0.5  
 0  0.6  
3   0  1  
4   0  1  
 0  1.5  
 A = B  
6   1  1  
7   3  
8   1  3  
9   0  4  
10   4  
11   0  5  
12   0  6  
 B > A 
13   0  5  
14   1  5  
15   2  10 
16   2  17  
17   0  17  
 B  
18  2  6  
19   2  7  
20   2  10  
21  2  10  
22   2  18  
23   2  18  
24  0* 17 

Splenomegaly was graded as follows: nonpalpable, 0; palpable to 10 cm below the costal margin, 1; and greater than 10 cm, 2. Disease duration was measured in years from the time of diagnosis.

*

This patient was asplenic at the time of diagnosis as assessed by computed axial tomography.

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