Table 1. Mean Plasma Concentrations of... | American Society of Hematology

Table 1.

Mean Plasma Concentrations of Coagulation Proteins and Inhibitors

Protein	Mean Plasma Concentration		E^1%280nm^†	Source
Protein	nmol/L	μg/mL	E^1%280nm^†	Source
Prothrombin	1,400	100	13.8	Plasma
Factor X	170	10	13.9	Plasma
Factor IX	90	5.1	13.2	Plasma
Factor XI	30	4.8	13.4	Plasma
Factor V	20	6.6	9.6	Plasma
Factor VII	10	0.5	13.9	Plasma
Factor VIII^*	0.7	0.2	—	Recombinant
Factor VIIa^*	0.1	0.005	—	Recombinant
Tissue factor^*	NA	NA	—	Recombinant
Antithrombin III	3,400	200	6.2	Plasma
Protein S	300	21	9.5	Plasma
Protein C	60	3.7	14.5	Plasma
TFPI^*	2.5	0.1	—	Recombinant
Tm^*	NA	NA	—	Recombinant

Protein	Mean Plasma Concentration		E^1%280nm^†	Source
Protein	nmol/L	μg/mL	E^1%280nm^†	Source
Prothrombin	1,400	100	13.8	Plasma
Factor X	170	10	13.9	Plasma
Factor IX	90	5.1	13.2	Plasma
Factor XI	30	4.8	13.4	Plasma
Factor V	20	6.6	9.6	Plasma
Factor VII	10	0.5	13.9	Plasma
Factor VIII^*	0.7	0.2	—	Recombinant
Factor VIIa^*	0.1	0.005	—	Recombinant
Tissue factor^*	NA	NA	—	Recombinant
Antithrombin III	3,400	200	6.2	Plasma
Protein S	300	21	9.5	Plasma
Protein C	60	3.7	14.5	Plasma
TFPI^*	2.5	0.1	—	Recombinant
Tm^*	NA	NA	—	Recombinant

Data for mean plasma concentrations from Kalafatis et al.75

Abbreviation: NA, not applicable (membrane protein).

Concentration provided by manufacturer.

Absorbance of 1% solution at 280 nm wavelength.