Differential Cell Counts in C57BL/6-lpr/lprSpleens Relative to Age-Matched Controls
. | Lymphocytes (%) . | Monocytes (%) . | Granulocytes Bands/Segmented (%) . | Erythroblasts (%) . | Immature Myeloid (%) . |
---|---|---|---|---|---|
C57BL/6-lpr/lpr | 43.1 ± 1.1 | 6.5 ± 0.8 | 30.4 ± 2.7 | 20.7 ± 3.9 | 6.5 ± 1.6 |
(137.9) | (20.8) | (97.3) | (66.2) | (20.8) | |
P < .001 | |||||
C57BL/6 | 82.3 ± 3.7 | 3.3 ± 0.4 | 3.6 ± 0.4 | 9.3 ± 2.8 | 1.1 ± 0.3 |
(90.5) | (3.6) | (4.0) | (10.2) | (1.2) |
. | Lymphocytes (%) . | Monocytes (%) . | Granulocytes Bands/Segmented (%) . | Erythroblasts (%) . | Immature Myeloid (%) . |
---|---|---|---|---|---|
C57BL/6-lpr/lpr | 43.1 ± 1.1 | 6.5 ± 0.8 | 30.4 ± 2.7 | 20.7 ± 3.9 | 6.5 ± 1.6 |
(137.9) | (20.8) | (97.3) | (66.2) | (20.8) | |
P < .001 | |||||
C57BL/6 | 82.3 ± 3.7 | 3.3 ± 0.4 | 3.6 ± 0.4 | 9.3 ± 2.8 | 1.1 ± 0.3 |
(90.5) | (3.6) | (4.0) | (10.2) | (1.2) |
Spleen cell suspensions from 6-month-old C57BL/6-lpr/lprmice and age-matched controls were cytocentrifuged and stained in May-Grünwald-Giemsa. Differential counts were performed on at least 200 cells per slide. Data are means ± SEM from 4 different mice per group. Average cell numbers per spleen (×106) are indicated in parentheses.