VH-Gene Rearrangements and Mutations in Monocytoid B Cells From 5 Cases of Piringer’s Lymphadenopathy
| Case No. . | Total No. of Isolated Cells . | IgR Unique/Identical . | IgR Without VH Mutations (%) . | IgR With VH Mutations (%) . | No. of VH Mutations/ Mutated Sequences . | ||
|---|---|---|---|---|---|---|---|
| Mean . | Percentage . | (range) . | |||||
| 1 | 105 | 24/1 | 16/24 (66%) | 8/24 (33%) | 7 | 4.6 | (1-14) |
| 2 | 53 | 16/2 | 13/16 (81.2%) | 3/16 (18.7%) | 2 | 1.3 | (1-4) |
| 3 | 90 | 21/0 | 18/21 (86%) | 3/21 (14.2%) | 6.6 | 4.3 | (1-14) |
| 4 | 31 | 14/0 | 7/14 (50%) | 7/14 (50%) | 5.5 | 3.7 | (5-7) |
| 5 | 48 | 15/2 | 13/15 (86.6%) | 2/15 (13.3%) | 5.6 | 3.8 | (4-9) |
| Total | 327 | 90/5 | 67/90 (74.4%) | 23/90 (25.6%) | 5.3 | 3.8 | (1-14) |
| Case No. . | Total No. of Isolated Cells . | IgR Unique/Identical . | IgR Without VH Mutations (%) . | IgR With VH Mutations (%) . | No. of VH Mutations/ Mutated Sequences . | ||
|---|---|---|---|---|---|---|---|
| Mean . | Percentage . | (range) . | |||||
| 1 | 105 | 24/1 | 16/24 (66%) | 8/24 (33%) | 7 | 4.6 | (1-14) |
| 2 | 53 | 16/2 | 13/16 (81.2%) | 3/16 (18.7%) | 2 | 1.3 | (1-4) |
| 3 | 90 | 21/0 | 18/21 (86%) | 3/21 (14.2%) | 6.6 | 4.3 | (1-14) |
| 4 | 31 | 14/0 | 7/14 (50%) | 7/14 (50%) | 5.5 | 3.7 | (5-7) |
| 5 | 48 | 15/2 | 13/15 (86.6%) | 2/15 (13.3%) | 5.6 | 3.8 | (4-9) |
| Total | 327 | 90/5 | 67/90 (74.4%) | 23/90 (25.6%) | 5.3 | 3.8 | (1-14) |
Abbreviations: IgR, Ig rearrangement; VH, variable region of the Ig heavy chain gene.