Characteristics of Individuals With MGUS
| Isotype . | Level of M-Component (g/L) . | Decrease of Other Ig* . | Follow-Up (mo)† . | % Plasma Cells . | IGH Configuration‡ . | Monosomy 13 (% plasma cells) . |
|---|---|---|---|---|---|---|
| IgGλ | 8.3 | No | 14 | 4 | YY | No (3) |
| IgAκ | 10.6 | No | 101 | 2 | YY | No (4) |
| IgGκ | 12 | M | 12 | 4 | t(11;14) | No (3) |
| IgAκ | 12 | No | 14 | 5 | t(11;14) | No (2) |
| IgAκ | 13.3 | No | 23 | 6 | YY | No (1) |
| IgAκ | 13.7 | No | 15 | 8 | YGO | No (2) |
| IgGκ | 14 | A | 98 | 4 | YY | Yes (18) |
| IgAκ | 14.4 | M | 19 | 8 | Y | No (2) |
| IgAκ | 14.6 | No | 17 | 2 | YGO | No (2) |
| IgGκ | 15 | No | 18 | 3 | YGO | Yes (33) |
| IgGκ | 17.5 | M | 12 | 2 | Y | No (3) |
| IgGλ | 17.8 | M | 66 | 6 | YGO | Yes (40) |
| IgGλ | 19.2 | M | 53 | 5 | YG | No (4) |
| IgGκ | 21 | No | 35 | 2 | YY | No (1) |
| IgGλ | 23 | M | 43 | 4 | t(11;14) | No (3) |
| IgGκ | 23.1 | M | 52 | 3 | YGO | No (4) |
| IgGκ | 23.5 | No | 74 | 3 | YGO | No (1) |
| IgGλ | 24.6 | No | 14 | 1 | t(4;14) | Yes (80) |
| IgGκ | 28 | No | 14 | 1 | YY | No (1) |
| Isotype . | Level of M-Component (g/L) . | Decrease of Other Ig* . | Follow-Up (mo)† . | % Plasma Cells . | IGH Configuration‡ . | Monosomy 13 (% plasma cells) . |
|---|---|---|---|---|---|---|
| IgGλ | 8.3 | No | 14 | 4 | YY | No (3) |
| IgAκ | 10.6 | No | 101 | 2 | YY | No (4) |
| IgGκ | 12 | M | 12 | 4 | t(11;14) | No (3) |
| IgAκ | 12 | No | 14 | 5 | t(11;14) | No (2) |
| IgAκ | 13.3 | No | 23 | 6 | YY | No (1) |
| IgAκ | 13.7 | No | 15 | 8 | YGO | No (2) |
| IgGκ | 14 | A | 98 | 4 | YY | Yes (18) |
| IgAκ | 14.4 | M | 19 | 8 | Y | No (2) |
| IgAκ | 14.6 | No | 17 | 2 | YGO | No (2) |
| IgGκ | 15 | No | 18 | 3 | YGO | Yes (33) |
| IgGκ | 17.5 | M | 12 | 2 | Y | No (3) |
| IgGλ | 17.8 | M | 66 | 6 | YGO | Yes (40) |
| IgGλ | 19.2 | M | 53 | 5 | YG | No (4) |
| IgGκ | 21 | No | 35 | 2 | YY | No (1) |
| IgGλ | 23 | M | 43 | 4 | t(11;14) | No (3) |
| IgGκ | 23.1 | M | 52 | 3 | YGO | No (4) |
| IgGκ | 23.5 | No | 74 | 3 | YGO | No (1) |
| IgGλ | 24.6 | No | 14 | 1 | t(4;14) | Yes (80) |
| IgGκ | 28 | No | 14 | 1 | YY | No (1) |
M means a decrease of IgM level and A a decrease of IgA level.
Follow-up from the diagnosis of MGUS.
Y means the presence of 1 yellow signal, corresponding to the colocalization of 1 green (G) and 1 orange (O) signal. Thus, YGO refers to the presence of 1 normal chromosome 14 and a second 1 bearing an illegitimate IGH rearrangement (separation of the green and orange signals).