Splenic T Cells in KIR2DL3 × HLA-Cw3 Double Transgenic Mice
Mice
.
No. of Cells/ Spleen (×106)
.
% CD3+ Cells/ Spleen
.
% CD3+KIR2DL3+ Cells/Spleen
.
Tg-HLA-Cw3
81.4 ± 7.9
39.4 ± 4.6
—
Tg-KIR2DL3 × HLA-Cw3
88.8 ± 16.5
42.2 ± 3.5
41.2 ± 3
Mice
.
No. of Cells/ Spleen (×106)
.
% CD3+ Cells/ Spleen
.
% CD3+KIR2DL3+ Cells/Spleen
.
Tg-HLA-Cw3
81.4 ± 7.9
39.4 ± 4.6
—
Tg-KIR2DL3 × HLA-Cw3
88.8 ± 16.5
42.2 ± 3.5
41.2 ± 3
Splenocytes were isolated from indicated mice and analyzed by flow cytometry for the cell surface expression of CD3ε and KIR2DL3. Data were obtained from 5 mice of each genotype.