Table 4.

Distribution of Different Types of Progenitors Present in 10-Day Cultures Initiated With LinCD34CD38 Adult Human Marrow or Mobilized Peripheral Blood Cells

Sample CFU-E BFU-E CFU-GEMM CFU-GM CFU-Mk
mPB1  0  2  0  48  0  
BM1  0  0  40  ND  
BM2  30  10  45  1,100  65 
BM3  15  90  50  1,800  120  
BM8  0  0  140  ND  
BM4  0  0  0  120  
BM5  24  36  0  380  ND  
BM6  12 72  12  820  ND  
BM7  84  0  0  420 ND 
Sample CFU-E BFU-E CFU-GEMM CFU-GM CFU-Mk
mPB1  0  2  0  48  0  
BM1  0  0  40  ND  
BM2  30  10  45  1,100  65 
BM3  15  90  50  1,800  120  
BM8  0  0  140  ND  
BM4  0  0  0  120  
BM5  24  36  0  380  ND  
BM6  12 72  12  820  ND  
BM7  84  0  0  420 ND 

Same experiments as described in Table 3. Values shown are the numbers of each type of CFC produced per 103linCD34CD38 cells originally placed in culture, as determined by assessment of a fraction of each 10 day culture harvest. CFU-E, BFU-E, CFU-GEMM, and CFU-GM assayed in methylcellulose cultures. CFU-Mk assayed in collagen cultures (see also note to Table 3).

Abbreviations: ND, not done; mPB, mobilized peripheral blood; BM, bone marrow (number indicates sample number).

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