Table 2. Hematologic Data and Spleen... | American Society of Hematology

Table 2.

Hematologic Data and Spleen Sizes in Mice Treated With L-744,832 at 80 mg/kg

Genotype^*	Treatment	No.	White Blood Cell Count (×10³ per μL)
Genotype^*	Treatment	No.	Start	2 wk	4 wk	Spleen (g)
Nfl+/+	None	3	10.7 ± 3.1	12 ± 6.1	10.7 ± 4.9	0.10 ± 0.06
Nfl+/+	L-744,832	2	11 ± 2.8	21 ± 9.9	15 ± 2.8	0.10 ± 0.00
Nfl−/−	None	2	26 ± 5.7	28 ± 11.3	26.5 ± 6.4	0.26 ± 0.24
Nfl−/−	L-744,832	3	29 ± 8.2	41.3 ± 41.3	26.3 ± 22.5	0.29 ± 0.06
Mix^†	None	2	24.5 ± 7.8	21^‡	18 ± 1.4	0.19 ± 0.02
Mix^†	L-744,832	2	17.5 ± 3.5	66.5 ± 7.8	48.5 ± 38.9	0.29 ± 0.17

Genotype^*	Treatment	No.	White Blood Cell Count (×10³ per μL)
Genotype^*	Treatment	No.	Start	2 wk	4 wk	Spleen (g)
Nfl+/+	None	3	10.7 ± 3.1	12 ± 6.1	10.7 ± 4.9	0.10 ± 0.06
Nfl+/+	L-744,832	2	11 ± 2.8	21 ± 9.9	15 ± 2.8	0.10 ± 0.00
Nfl−/−	None	2	26 ± 5.7	28 ± 11.3	26.5 ± 6.4	0.26 ± 0.24
Nfl−/−	L-744,832	3	29 ± 8.2	41.3 ± 41.3	26.3 ± 22.5	0.29 ± 0.06
Mix^†	None	2	24.5 ± 7.8	21^‡	18 ± 1.4	0.19 ± 0.02
Mix^†	L-744,832	2	17.5 ± 3.5	66.5 ± 7.8	48.5 ± 38.9	0.29 ± 0.17

Refers to genotype of transplanted fetal liver cells.

Refers to mice injected with a mix of Nfl+/+ andNfl−/− fetal liver cells (see text).

Data were available from only 1 mouse at this time point.