Table 3. Association of Graft Failure... | American Society of Hematology

Table 3.

Association of Graft Failure With T-Cell Depletion With Stratification According to Underlying Disease and Donor HLA Disparity

Risk Group	T-Cell Depletion	Graft Failure
Risk Group	T-Cell Depletion	Yes	No
High	Yes	2	2
	No	11	41
Low	Yes	4	17
	No	10	501

Risk Group	T-Cell Depletion	Graft Failure
Risk Group	T-Cell Depletion	Yes	No
High	Yes	2	2
	No	11	41
Low	Yes	4	17
	No	10	501

The high-risk group includes patients with CML who had a donor with disparity for multiple class I alleles. All other patients are categorized in the low-risk group. Results for marrow transplantation without T-cell depletion in patients with CML have been reported previously.10 Graft failure in controls was defined according to published criteria.21 All patients were prepared for transplantation with a conditioning regimen of cyclophosphamide and 12.0 to 15.75 Gy TBI and received methotrexate plus cyclosporine for GVHD prophylaxis.

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