Table 2. Effect of AR545C or... | American Society of Hematology

Table 2.

Effect of AR545C or S-nitroso-AR545 on Platelet Interaction With ECM Under Flow Conditions

	Control	AR545C			S-nitroso-AR545C
	Control	0.5 μmol/L	1.0 μmol/L	1.5 μmol/L	0.5 μmol/L	1.0 μmol/L	1.5 μmol/L
Surface coverage (%)	28.4 ± 5.9	12.9 ± 1.1	10.0 ± 1.4	7.5 ± 1.8	10.2 ± 0.9	5.5 ± 1.3^*	4.8 ± 1.1^*
					P = .09^†	P = .05^†	P = .004^†
Average size of aggregates (μm²)	47.2 ± 15.2	36.2 ± 8.1	21.4 ± 5.7	17.1 ± 1.1	18.7 ± 2.2	13.0 ± 3.1^*	11.5 ± 0.7^*
					P = .07^†	P = .2^†	P = .003^†

	Control	AR545C			S-nitroso-AR545C
	Control	0.5 μmol/L	1.0 μmol/L	1.5 μmol/L	0.5 μmol/L	1.0 μmol/L	1.5 μmol/L
Surface coverage (%)	28.4 ± 5.9	12.9 ± 1.1	10.0 ± 1.4	7.5 ± 1.8	10.2 ± 0.9	5.5 ± 1.3^*	4.8 ± 1.1^*
					P = .09^†	P = .05^†	P = .004^†
Average size of aggregates (μm²)	47.2 ± 15.2	36.2 ± 8.1	21.4 ± 5.7	17.1 ± 1.1	18.7 ± 2.2	13.0 ± 3.1^*	11.5 ± 0.7^*
					P = .07^†	P = .2^†	P = .003^†

Results are expressed as mean ± SEM of 3 determinations.

P < .05 compared with control.

Compared with the same concentration of AR545C.