Table 3.

Gender Differences Based on Either Ig V Gene Mutation Status or the Percentages of CD38+ B-CLL Cells

Unmutated Mutated
Male3-150 91.7% (22/24) 52.2% (12/23)  
Female3-150 8.3% (2/24)  47.8% (11/23) 
 P = .0033-150 
Male:female ratio  11.0:1  1.1:1 
 ≥30% CD38+ B-CLL Cells <30% CD38+ B-CLL Cells  
Male3-150 88.2% (15/17)  52.6% (10/19)  
Female3-150 11.8% (2/17) 47.4% (9/19)  
 P = .0313-150 
Male:female ratio   7.5:1  1.1:1 
Unmutated Mutated
Male3-150 91.7% (22/24) 52.2% (12/23)  
Female3-150 8.3% (2/24)  47.8% (11/23) 
 P = .0033-150 
Male:female ratio  11.0:1  1.1:1 
 ≥30% CD38+ B-CLL Cells <30% CD38+ B-CLL Cells  
Male3-150 88.2% (15/17)  52.6% (10/19)  
Female3-150 11.8% (2/17) 47.4% (9/19)  
 P = .0313-150 
Male:female ratio   7.5:1  1.1:1 
F3-150

Statistically significant difference in gender distribution between the unmutated and mutated groups and between the ≥30% CD38+ and <30% CD38+ groups (2-tailed Fisher’s Exact test).

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