Table 2.

Comparison of Modified Rai Stage at Diagnosis With Ig V Gene Mutation Status and the Percentages of CD38+ B-CLL Cells

Stage Unmutated Mutated
Low* 22.7% (5/22) 52.4% (11/21)  
Intermediate* 72.7% (16/22) 42.9% (9/21)  
High  4.6% (1/22)  4.7% (1/21) 
 P = .123  
 ≥30% CD38+ B-CLL Cells <30% CD38+ B-CLL Cells  
Low 20.0% (3/15)  50.0% (9/18)  
Intermediate 73.3% (11/15)  50.0% (9/18)  
High  6.7% (1/15) 0.0% (0/18)  
 P = .138  
Stage Unmutated Mutated
Low* 22.7% (5/22) 52.4% (11/21)  
Intermediate* 72.7% (16/22) 42.9% (9/21)  
High  4.6% (1/22)  4.7% (1/21) 
 P = .123  
 ≥30% CD38+ B-CLL Cells <30% CD38+ B-CLL Cells  
Low 20.0% (3/15)  50.0% (9/18)  
Intermediate 73.3% (11/15)  50.0% (9/18)  
High  6.7% (1/15) 0.0% (0/18)  
 P = .138  
*

Comparison of V gene mutation status among patients in the low and intermediate risk categories (P = .058; 2-tailed Fisher’s Exact test).

Comparison of CD38 expression among patients in the low and intermediate risk categories (P = .147; 2-tailed Fisher’s Exact test).

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