Distributions of Mutations in Tumor-Derived VH Sequences
Patient . | Region . | Expected . | Observed . | P4-150 . | ||
---|---|---|---|---|---|---|
R . | S . | R . | S . | |||
1 | FR | 42 | 15 | 29 | 23 | <.01 |
CDR | 13 | 3 | 16 | 5 | .07 | |
2 | FR | 33 | 11 | 19 | 15 | <.01 |
CDR | 9 | 2 | 15 | 6 | .02 | |
3 | FR | 35 | 13 | 16 | 16 | <.01 |
CDR | 11 | 2 | 5 | 4 | .12 | |
4 | FR | 31 | 11 | 23 | 14 | .02 |
CDR | 9 | 2 | 10 | 5 | .14 | |
5 | FR | 26 | 9 | 14 | 16 | <.01 |
CDR | 8 | 2 | 10 | 5 | .11 |
Patient . | Region . | Expected . | Observed . | P4-150 . | ||
---|---|---|---|---|---|---|
R . | S . | R . | S . | |||
1 | FR | 42 | 15 | 29 | 23 | <.01 |
CDR | 13 | 3 | 16 | 5 | .07 | |
2 | FR | 33 | 11 | 19 | 15 | <.01 |
CDR | 9 | 2 | 15 | 6 | .02 | |
3 | FR | 35 | 13 | 16 | 16 | <.01 |
CDR | 11 | 2 | 5 | 4 | .12 | |
4 | FR | 31 | 11 | 23 | 14 | .02 |
CDR | 9 | 2 | 10 | 5 | .14 | |
5 | FR | 26 | 9 | 14 | 16 | <.01 |
CDR | 8 | 2 | 10 | 5 | .11 |
P is the probability of obtaining the number of R mutations by chance.