Antibody Specificity and Comparison of the Results Obtained With Indirect GIFT and MAIGA
| Patients with primary AIN | ||
| Indirect GIFT | MAIGA | |
| NA1 (n = 13)3-150 | NA1 | (n = 3) |
| NA2 | (n = 2)3-151 | |
| NA1 and NA2 | (n = 2)3-152 | |
| Negative | (n = 6) | |
| NA2 (n = 2)3-153 | NA2 | (n = 2) |
| pan FcγRIIIb (n = 1) | NA1 and NA2 | (n = 1) |
| inconclusive (n = 2) | NA1 | (n = 1) |
| NA1 + NA23-155 | (n = 1) | |
| Patients with secondary AIN | ||
| Pan FcγRIIIb (n = 5)3-154 | NA1 and NA2# | (n = 1) |
| NA1 | (n = 1) | |
| Negative | (n = 3) |
| Patients with primary AIN | ||
| Indirect GIFT | MAIGA | |
| NA1 (n = 13)3-150 | NA1 | (n = 3) |
| NA2 | (n = 2)3-151 | |
| NA1 and NA2 | (n = 2)3-152 | |
| Negative | (n = 6) | |
| NA2 (n = 2)3-153 | NA2 | (n = 2) |
| pan FcγRIIIb (n = 1) | NA1 and NA2 | (n = 1) |
| inconclusive (n = 2) | NA1 | (n = 1) |
| NA1 + NA23-155 | (n = 1) | |
| Patients with secondary AIN | ||
| Pan FcγRIIIb (n = 5)3-154 | NA1 and NA2# | (n = 1) |
| NA1 | (n = 1) | |
| Negative | (n = 3) |
Three sera were not available for testing.
One serum showed only positive results with MEM154 and not with 3G8.
One serum showed negative results with 3G8 and only positive results with BW209/2, both with homozygous NA1- and NA2-positive neutrophils.
For 1 patient, no material was available to perform both the NA1- and the NA2-MAIGA.
In the MAIGA with NA2-positive neutrophils, a positive result was obtained with MEM154, but not with 3G8.
Two sera were not available for testing.
#Positive results were obtained with BW209/2, but not with 3G8, both in the NA1- and in the NA2-MAIGA.