Table 1.

Percentage of Donors Mediating Directed Lysis of P815 Target Cells

MoAb Specificity % Active Donors*N
CD38  64 34  
CD16  85  27  
MHC I  18  11  
CD11a  0   5 
MoAb Specificity % Active Donors*N
CD38  64 34  
CD16  85  27  
MHC I  18  11  
CD11a  0   5 
*

Percentages of donors in which the indicated MoAb increased lysis more than 1.5-fold over natural cytotoxicity at at least 2 different E:T ratios.

Number of donors tested. IL-2–activated PBL were used as effectors.

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