Inhibition of PDTC-Induced Apoptosis by DEVD-CHO
| PDTC . | DEVD-CHO . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|---|
| (−) | (−) | 3.2 ± 0.2 | 4.0 ± 0.3 |
| (−) | (+) | 2.7 ± 0.3 | 3.7 ± 0.3 |
| (+) | (−) | 49.5 ± 3.0 | 52.5 ± 4.0 |
| (+) | (+) | 8.9 ± 0.63-150 | 8.8 ± 0.53-150 |
| PDTC . | DEVD-CHO . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|---|
| (−) | (−) | 3.2 ± 0.2 | 4.0 ± 0.3 |
| (−) | (+) | 2.7 ± 0.3 | 3.7 ± 0.3 |
| (+) | (−) | 49.5 ± 3.0 | 52.5 ± 4.0 |
| (+) | (+) | 8.9 ± 0.63-150 | 8.8 ± 0.53-150 |
Jurkat and JPX-9 cells were cultured with or without PDTC, in the presence or absence of DEVD-CHO, for 24 hours. After incubation, the percentage of cells with hypodiploid DNA was examined by flow cytometry.
P < .01 compared with data without DEVD-CHO. Data are mean ± SD of 5 experiments.