Induction of Apoptosis of Jurkat and JPX-9 Cells by NAC
| NAC (mmol/L) . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|
| 0 | 3.5 ± 0.2 | 3.4 ± 0.2 |
| 1 | 10.5 ± 1.0* | 12.8 ± 1.1* |
| 10 | 26.2 ± 2.1* | 27.9 ± 1.8* |
| 50 | 40.5 ± 2.5* | 42.9 ± 3.0* |
| 100 | 43.5 ± 3.1* | 44.0 ± 2.9* |
| NAC (mmol/L) . | Jurkat (%) . | JPX-9 (%) . |
|---|---|---|
| 0 | 3.5 ± 0.2 | 3.4 ± 0.2 |
| 1 | 10.5 ± 1.0* | 12.8 ± 1.1* |
| 10 | 26.2 ± 2.1* | 27.9 ± 1.8* |
| 50 | 40.5 ± 2.5* | 42.9 ± 3.0* |
| 100 | 43.5 ± 3.1* | 44.0 ± 2.9* |
Jurkat and JPX-9 cells were incubated with different concentrations of NAC for 24 hours. After incubation, the percentage of cells with hypodiploid DNA was examined by flow cytometry.
P < .01 compared with control data (absence of NAC). Data are mean ± SD of 5 experiments.