Light Chain Production by the Mice and Microscopic Analysis of the Kidneys
| . | Mice . | Serum κ Chain (μg/mL) . | Urine κ Chain (μg/mL) . | κ Chain Crystals . | Myeloma Casts . |
|---|---|---|---|---|---|
| CHEB | 1 | 22 | 64 | − | − |
| 2 | 16 | 41 | − | − | |
| 3 | 6 | 138 | − | − | |
| 4 | 230 | 6500 | + | − | |
| 5 | 1040 | 1931 | + | − | |
| 6 | 82 | 130 | + | − | |
| 7 | 120 | 4630 | + | − | |
| 8 | 156 | 6328 | + | − | |
| 9 | 140 | 2530 | + | − | |
| 10 | ND | ND | + | − | |
| 269 | 1 | 82 | 517 | − | − |
| 2 | 120 | ND | − | + | |
| 3 | 65 | 44 | − | + | |
| 4 | 207 | ND | − | + | |
| 5 | 90 | 455 | − | + | |
| 6 | 121 | 1054 | − | + | |
| 7 | 25 | 120 | − | − | |
| 8 | 32 | 159 | − | − | |
| 9 | 13 | 159 | − | − | |
| 10 | ND | ND | − | − | |
| CHEBm30 | 1 | 91 | 328 | − | + |
| 2 | 99 | 338 | − | − | |
| 3 | 12.65 | ND | − | − | |
| 4 | 45.1 | ND | − | − | |
| 5 | 7.9 | 370 | − | − | |
| 6 | 740 | 89.2 | − | − | |
| 7 | 41.7 | 735 | − | − | |
| 8 | 12.4 | 258 | − | − | |
| 9 | 22.3 | 501 | − | ± (rare) | |
| CHEBm94 | 1 | 81 | 1160 | − | − |
| 2 | 112 | 372 | − | − | |
| 3 | 147 | 3080 | − | − | |
| 4 | 257 | 2980 | − | − | |
| 5 | 172 | 3000 | − | − | |
| 6 | 297 | 1400 | − | − | |
| 7 | 253 | 3050 | − | − | |
| 269m30 | 1 | 82 | 793 | − | − |
| 2 | 30.3 | 670 | − | + | |
| 3 | 28 | 840 | − | + | |
| 4 | 8 | 205 | − | − | |
| 5 | 14 | 206 | − | + | |
| 6 | 28.6 | ND | − | − | |
| 7 | 30.6 | ND | − | + | |
| 8 | 35.6 | ND | − | − |
| . | Mice . | Serum κ Chain (μg/mL) . | Urine κ Chain (μg/mL) . | κ Chain Crystals . | Myeloma Casts . |
|---|---|---|---|---|---|
| CHEB | 1 | 22 | 64 | − | − |
| 2 | 16 | 41 | − | − | |
| 3 | 6 | 138 | − | − | |
| 4 | 230 | 6500 | + | − | |
| 5 | 1040 | 1931 | + | − | |
| 6 | 82 | 130 | + | − | |
| 7 | 120 | 4630 | + | − | |
| 8 | 156 | 6328 | + | − | |
| 9 | 140 | 2530 | + | − | |
| 10 | ND | ND | + | − | |
| 269 | 1 | 82 | 517 | − | − |
| 2 | 120 | ND | − | + | |
| 3 | 65 | 44 | − | + | |
| 4 | 207 | ND | − | + | |
| 5 | 90 | 455 | − | + | |
| 6 | 121 | 1054 | − | + | |
| 7 | 25 | 120 | − | − | |
| 8 | 32 | 159 | − | − | |
| 9 | 13 | 159 | − | − | |
| 10 | ND | ND | − | − | |
| CHEBm30 | 1 | 91 | 328 | − | + |
| 2 | 99 | 338 | − | − | |
| 3 | 12.65 | ND | − | − | |
| 4 | 45.1 | ND | − | − | |
| 5 | 7.9 | 370 | − | − | |
| 6 | 740 | 89.2 | − | − | |
| 7 | 41.7 | 735 | − | − | |
| 8 | 12.4 | 258 | − | − | |
| 9 | 22.3 | 501 | − | ± (rare) | |
| CHEBm94 | 1 | 81 | 1160 | − | − |
| 2 | 112 | 372 | − | − | |
| 3 | 147 | 3080 | − | − | |
| 4 | 257 | 2980 | − | − | |
| 5 | 172 | 3000 | − | − | |
| 6 | 297 | 1400 | − | − | |
| 7 | 253 | 3050 | − | − | |
| 269m30 | 1 | 82 | 793 | − | − |
| 2 | 30.3 | 670 | − | + | |
| 3 | 28 | 840 | − | + | |
| 4 | 8 | 205 | − | − | |
| 5 | 14 | 206 | − | + | |
| 6 | 28.6 | ND | − | − | |
| 7 | 30.6 | ND | − | + | |
| 8 | 35.6 | ND | − | − |