Table 3.

Vector Expression in 2°CFU-S

Primary Recipient No.3-150MNDeGFPSN LeGFPSN
Expression in 1° BM Vector3-151 (n) Expression3-152Expression in 1° BM Vector3-151 (n) Expression3-152
1  60%  13/13  13/13  0.4% 13/15  0/13  
(8 wks)   (3)   (4)  
2  78.5%  6/6 6/6  ND  ND  ND  
(6 mos)   (2)  
65.1%  8/8  8/8  8.4%  8/12  0/8   
(4 mos)  (3)    (3)  
4  84.1% 11/11  11/11  4.4% 12/16  0/12  
(6 mos)   (4)   (4)  
5  40.5%  16/16 16/16  31%  13/13 0/13  
(6 mos)   (4)    (4) 
 
1-5   54/54  54/54   46/56 0/46  
  100%  100%   82% 0% 
Primary Recipient No.3-150MNDeGFPSN LeGFPSN
Expression in 1° BM Vector3-151 (n) Expression3-152Expression in 1° BM Vector3-151 (n) Expression3-152
1  60%  13/13  13/13  0.4% 13/15  0/13  
(8 wks)   (3)   (4)  
2  78.5%  6/6 6/6  ND  ND  ND  
(6 mos)   (2)  
65.1%  8/8  8/8  8.4%  8/12  0/8   
(4 mos)  (3)    (3)  
4  84.1% 11/11  11/11  4.4% 12/16  0/12  
(6 mos)   (4)   (4)  
5  40.5%  16/16 16/16  31%  13/13 0/13  
(6 mos)   (4)    (4) 
 
1-5   54/54  54/54   46/56 0/46  
  100%  100%   82% 0% 

Abbreviation: (n), number of secondary transplant recipients; ND, not done.

F3-150

Time after 1° transplant when 2° transplant was performed.

F3-151

Number of CFU-S PCR (+) for vector DNA/number of CFU-S tested.

F3-152

Number of CFU-S (+) for eGFP expression by FACS/number of CFU-S tested.

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