Table 2.

eGFP Expression and Vector Copy Number Per Cell

Bone Marrow Spleen Thymus BloodGranulocytes in Bone Marrow B Cells in Spleen T Cells in Thymus
LEGFPSN  
 % eGFP(+) cells* (n) 5.5 ± 2.4 (14)  4.7 ± 3.9 (15)  2.7 ± 2.4 (13)  3.6 ± 1.4 (8)  7.2 ± 3.9 (7)  4.1 ± 0.9 (8)  8.6 ± 3.4  (7)  
 Vector Copy#/cell (n)  1.4 ± 0.6 (14)  2 ± 0.7 (15)  0.7 ± 0.4 (13)  1.04 ± 0.9 (8)  3.9 ± 2.3 (7)  4.7 ± 1.5 (8)  0.9 ± 0.4  (7)  
MNDeGFPSN  
 % eGFP(+) cells* (n) 26.3 ± 6.2 (17)  30.6 ± 4.9 (17)  29.8 ± 8.8 (15)  31.6 ± 9.1 (9)  28.9 ± 9.1 (8)  35.2 ± 8.3 (6)  31.9 ± 10.2 (12)  
 Vector Copy#/cell (n)  1.5 ± 0.5 (17)  1.8 ± 0.7 (17)  2 ± 0.7 (15)  1.5 ± 0.8 (9)  2.3 ± 0.9 (8)  1.7 ± 0.8 (6)  1.4 ± 0.6 (12)  
Bone Marrow Spleen Thymus BloodGranulocytes in Bone Marrow B Cells in Spleen T Cells in Thymus
LEGFPSN  
 % eGFP(+) cells* (n) 5.5 ± 2.4 (14)  4.7 ± 3.9 (15)  2.7 ± 2.4 (13)  3.6 ± 1.4 (8)  7.2 ± 3.9 (7)  4.1 ± 0.9 (8)  8.6 ± 3.4  (7)  
 Vector Copy#/cell (n)  1.4 ± 0.6 (14)  2 ± 0.7 (15)  0.7 ± 0.4 (13)  1.04 ± 0.9 (8)  3.9 ± 2.3 (7)  4.7 ± 1.5 (8)  0.9 ± 0.4  (7)  
MNDeGFPSN  
 % eGFP(+) cells* (n) 26.3 ± 6.2 (17)  30.6 ± 4.9 (17)  29.8 ± 8.8 (15)  31.6 ± 9.1 (9)  28.9 ± 9.1 (8)  35.2 ± 8.3 (6)  31.9 ± 10.2 (12)  
 Vector Copy#/cell (n)  1.5 ± 0.5 (17)  1.8 ± 0.7 (17)  2 ± 0.7 (15)  1.5 ± 0.8 (9)  2.3 ± 0.9 (8)  1.7 ± 0.8 (6)  1.4 ± 0.6 (12)  

Abbreviation: (n), number of animals analyzed.

*

Percentage of eGFP(+) cells of tissues subjected to copy number/cell analysis.

Vector copy numbers between LeGFPSN and MNDeGFPSN are not statistically significantly different.

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