Table 1.

Clinical Characteristics of B-Cell CLL Patients

Patient No. Diagnosis Modified Rai StagePrevious Treatment Active Disease*Fludarabine Refractory
1  CLL  IR  None  Yes  NA  
2  CLL IR  None  No  NA  
3  CLL  IR  None  No NA  
4  CLL  IR  None  Yes  NA  
5  CLL HR  C + P, Flu, CHOP  Yes  Yes  
6  CLL  IR None  No  NA  
7  CLL  HR  C + P, 9AC  Yes NA  
8  CLL  IR  None  Yes  NA  
9  CLL HR  C + P, Flu, 2CDA  Yes  Yes  
10  CLL  IR None  Yes  NA 
Patient No. Diagnosis Modified Rai StagePrevious Treatment Active Disease*Fludarabine Refractory
1  CLL  IR  None  Yes  NA  
2  CLL IR  None  No  NA  
3  CLL  IR  None  No NA  
4  CLL  IR  None  Yes  NA  
5  CLL HR  C + P, Flu, CHOP  Yes  Yes  
6  CLL  IR None  No  NA  
7  CLL  HR  C + P, 9AC  Yes NA  
8  CLL  IR  None  Yes  NA  
9  CLL HR  C + P, Flu, 2CDA  Yes  Yes  
10  CLL  IR None  Yes  NA 

Abbreviations: IR, intermediate risk; HR, high risk; C, chlorambucil; P, prednisone; Flu, fludarabine; CHOP, cyclophosphamide, doxorubicin, vincristine, and prednisone; 9AC, 9-aminocamptothecin; 2CDA, cladribine; NA, not applicable.

*

Active disease defined as required treatment within 2 months of donating cells.

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