Table 3. Side Effects of As 2 O 3 in 58... | American Society of Hematology

Table 3.

Side Effects of As₂O₃ in 58 APL Patients

Side Effects	Group	Newly Diagnosed Patients				Relapsed Patients				P Value
Side Effects	Grade	1	2	3	4	1	2	3	4	P Value
Skin reaction		1	2	0	0	8	4^3-150	0	0	NS
Gastrointestinal reaction		4	0	0	0	10^3-151	0	0	0	NS
Cardiac dysfunction		1	0	0	0	8	0	0	0	NS
Facial edema and neuropathy		1	0	0	0	5	0	0	0	NS
Liver dysfunction		2	3	2	0	14	1	0	0	.001

Side Effects	Group	Newly Diagnosed Patients				Relapsed Patients				P Value
Side Effects	Grade	1	2	3	4	1	2	3	4	P Value
Skin reaction		1	2	0	0	8	4^3-150	0	0	NS
Gastrointestinal reaction		4	0	0	0	10^3-151	0	0	0	NS
Cardiac dysfunction		1	0	0	0	8	0	0	0	NS
Facial edema and neuropathy		1	0	0	0	5	0	0	0	NS
Liver dysfunction		2	3	2	0	14	1	0	0	.001

Abbreviation: NS, not significant.

Including 1 patient received As₂O₃ + ATRA concurrently.

Including 2 patients received As₂O₃ + chemotherapy.