Outcome for Infants With ALL According to Prednisone Response
| No Infants . | All Infants (105) . | PGR (78) . | PPR (27) . | |||
|---|---|---|---|---|---|---|
| n . | (%) . | n . | (%) . | n . | (%) . | |
| CR achieved | 100 | (95) | 75 | (96) | 25 | (93) |
| 1st CCR | 47 | (45) | 43 | (55) | 4 | (15) |
| pEFS ± SE (%) | 43 ± 5 | 53 ± 6 | 15 ± 7 | |||
| 6 yr-survival ± SE (%) | 48 ± 6 | 65 ± 6 | 22 ± 8 | |||
| Events | 58 | (55) | 35 | (45) | 23 | (85) |
| Induction failure | 5 | (5) | 3 | (4) | 2 | (7) |
| Death in CR | 4 | (4) | 13-150 | (1) | 33-151 | (11) |
| Relapse | 49 | (47) | 31 | (40) | 18 | (67) |
| Site of relapse | ||||||
| BM | 26 | 13 | 13 | |||
| CNS | 9 | 4 | 5 | |||
| Testes | 3 | 3 | — | |||
| BM/CNS | 10 | 10 | — | |||
| BM/testes | 1 | 1 | — | |||
| Second malignancy | 13-152 | 13-152 | — | |||
| No Infants . | All Infants (105) . | PGR (78) . | PPR (27) . | |||
|---|---|---|---|---|---|---|
| n . | (%) . | n . | (%) . | n . | (%) . | |
| CR achieved | 100 | (95) | 75 | (96) | 25 | (93) |
| 1st CCR | 47 | (45) | 43 | (55) | 4 | (15) |
| pEFS ± SE (%) | 43 ± 5 | 53 ± 6 | 15 ± 7 | |||
| 6 yr-survival ± SE (%) | 48 ± 6 | 65 ± 6 | 22 ± 8 | |||
| Events | 58 | (55) | 35 | (45) | 23 | (85) |
| Induction failure | 5 | (5) | 3 | (4) | 2 | (7) |
| Death in CR | 4 | (4) | 13-150 | (1) | 33-151 | (11) |
| Relapse | 49 | (47) | 31 | (40) | 18 | (67) |
| Site of relapse | ||||||
| BM | 26 | 13 | 13 | |||
| CNS | 9 | 4 | 5 | |||
| Testes | 3 | 3 | — | |||
| BM/CNS | 10 | 10 | — | |||
| BM/testes | 1 | 1 | — | |||
| Second malignancy | 13-152 | 13-152 | — | |||