Table 3.

Overexpression of Individual TCRBV Gene Segments in CD4+ and CD8+ T Cells, Respectively, of 10 CLL Patients Compared With Age-Matched Healthy Controls

Patients BV-CD4 BV-CD8
CLL 2   7  
CLL 3   2, 3, 4, 5S1, 6S1-3, 8, 9  2, 4, 5S1  
CLL 7   None  None 
CLL 9   4  2, 5S1  
CLL 10  7  1, 2, 17  
CLL 11 7  None  
CLL 13  2, 6S1-3, 7, 18  None  
CLL 14 2, 4, 5S1, 6S1-3, 8  None  
CLL 15  None  2, 5S1, 7, 8 
CLL 16  None  5S1, 8  
  11 
Patients BV-CD4 BV-CD8
CLL 2   7  
CLL 3   2, 3, 4, 5S1, 6S1-3, 8, 9  2, 4, 5S1  
CLL 7   None  None 
CLL 9   4  2, 5S1  
CLL 10  7  1, 2, 17  
CLL 11 7  None  
CLL 13  2, 6S1-3, 7, 18  None  
CLL 14 2, 4, 5S1, 6S1-3, 8  None  
CLL 15  None  2, 5S1, 7, 8 
CLL 16  None  5S1, 8  
  11 

A TCRBV gene segment was regarded as overexpressed when the relative frequency was more than the mean + 3 SD for that of the control donors (n = 9).

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