Clinical and Pathologic Characteristics of 352 AML Cases on Study 8600
| . | Median . | Range . |
|---|---|---|
| Age (yr) | 44 | 17-69 |
| Marrow blasts (%) | 78 | 0-99 |
| WBC count (×109/L) | 37.4 | 0.7-416 |
| Peripheral blasts (%) | 51 | 0-99 |
| Peripheral blasts (×109/L) | 12.3 | 0-378 |
| Hemoglobin (g/dL) | 9.3 | 4.5-15.0 |
| Platelets (×109/L) | 52 | 3-700 |
| No. | Percent | |
| Female | 145 | 41 |
| Male | 207 | 59 |
| FAB (central review) | ||
| M1 | 72 | 20 |
| M2 | 145 | 41 |
| M3 | 30 | 9 |
| M4 | 54 | 15 |
| M5 | 31 | 9 |
| M6 | 2 | 1 |
| M7 | 3 | 1 |
| M0 | 7 | 2 |
| M0/M5 | 1 | 0.3 |
| Myeloid, NOS | 7 | 2 |
| Treatment arm | ||
| Ara-C (200 mg/m2) + DNR | 245 | 70 |
| Ara-C (2.0 g/m2) + DNR | 90 | 26 |
| Ara-C (3.0 g/m2) + DNR | 17 | 5 |
| . | Median . | Range . |
|---|---|---|
| Age (yr) | 44 | 17-69 |
| Marrow blasts (%) | 78 | 0-99 |
| WBC count (×109/L) | 37.4 | 0.7-416 |
| Peripheral blasts (%) | 51 | 0-99 |
| Peripheral blasts (×109/L) | 12.3 | 0-378 |
| Hemoglobin (g/dL) | 9.3 | 4.5-15.0 |
| Platelets (×109/L) | 52 | 3-700 |
| No. | Percent | |
| Female | 145 | 41 |
| Male | 207 | 59 |
| FAB (central review) | ||
| M1 | 72 | 20 |
| M2 | 145 | 41 |
| M3 | 30 | 9 |
| M4 | 54 | 15 |
| M5 | 31 | 9 |
| M6 | 2 | 1 |
| M7 | 3 | 1 |
| M0 | 7 | 2 |
| M0/M5 | 1 | 0.3 |
| Myeloid, NOS | 7 | 2 |
| Treatment arm | ||
| Ara-C (200 mg/m2) + DNR | 245 | 70 |
| Ara-C (2.0 g/m2) + DNR | 90 | 26 |
| Ara-C (3.0 g/m2) + DNR | 17 | 5 |