Table 2.

Changes in the Platelet Mobility Index Around the Transitional Time Point From 1,500 s−1 to 4,500 s−1 During Blood Perfusion of a BSS, vWD Type 3, and Af Patient*

Shear Rate: 1,500 s−14,500 s−1
BSS-1   11.2 ± 2.2  → 9.8 ± 1.9  
vWD type 3   10.6 ± 1.6  → 9.6 ± 1.4  
Af-1   9 ± 2.5  → 42.3±6.5̲ 
Control  12 ± 1.6  →  9 ± 2.4 
Shear Rate: 1,500 s−14,500 s−1
BSS-1   11.2 ± 2.2  → 9.8 ± 1.9  
vWD type 3   10.6 ± 1.6  → 9.6 ± 1.4  
Af-1   9 ± 2.5  → 42.3±6.5̲ 
Control  12 ± 1.6  →  9 ± 2.4 
*

Data are from the experiments described in the legends to Fig 5(BSS and type 3 vWD) and Fig 6 (Af) and obtained at 10 seconds before (1,500 s−1) and after (4,500 s−1) the shear rate transition. Each platelet mobility index (during 2 seconds; Materials and Methods) represents the mean ± SD of five index values derived from five nonoverlapping areas (110 × 73 μm) in a single frame. Note that the platelet mobility index of Af (underlined) greatly increased after the shear rate elevation, suggesting the breakdown of platelet immobilization to the surface once established.

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