Evaluation of Platelets Adhering to a Collagen-Coated Surface at 1 Minute and 7 Minutes of Perfusion Under Low or High Shear Rate Conditions in Various Congenital Platelet Aggregation Disorders
| Patients . | Perfusion Time: . | Low Shear (50 s−1) . | High Shear (1,500 s−1) . | ||||
|---|---|---|---|---|---|---|---|
| 1 . | → . | 7 . | 1 . | → . | 7 (minutes) . | ||
| BSS-1 | 36.2* | 437 | 1 | 2.1 | |||
| BSS-2 | 49.7 | 417.3 | 0.8 | 2 | |||
| GTA-1 | 15.3 | 12.9 | 16.5 | 24.9 | |||
| GTA-2 | 29.6 | 33.7 | 33.2 | 35.9 | |||
| GTA-3 | 12.3 | 13.5 | 11.8 | 12 | |||
| vWD type 3 | 29.8 | 465 | 1.6 | 1.5 | |||
| Af-1 | 24.2 | 316.1 | 39.3 | 3006.2 | |||
| Af-2 | 43 | 285.2 | 37.4 | 2522 | |||
| Control (n = 10) | 22.2 ± 14.3 | 368.6 ± 108.5 | 30.9 ± 20.4 | 2278.4 ± 544.5 | |||
| Patients . | Perfusion Time: . | Low Shear (50 s−1) . | High Shear (1,500 s−1) . | ||||
|---|---|---|---|---|---|---|---|
| 1 . | → . | 7 . | 1 . | → . | 7 (minutes) . | ||
| BSS-1 | 36.2* | 437 | 1 | 2.1 | |||
| BSS-2 | 49.7 | 417.3 | 0.8 | 2 | |||
| GTA-1 | 15.3 | 12.9 | 16.5 | 24.9 | |||
| GTA-2 | 29.6 | 33.7 | 33.2 | 35.9 | |||
| GTA-3 | 12.3 | 13.5 | 11.8 | 12 | |||
| vWD type 3 | 29.8 | 465 | 1.6 | 1.5 | |||
| Af-1 | 24.2 | 316.1 | 39.3 | 3006.2 | |||
| Af-2 | 43 | 285.2 | 37.4 | 2522 | |||
| Control (n = 10) | 22.2 ± 14.3 | 368.6 ± 108.5 | 30.9 ± 20.4 | 2278.4 ± 544.5 | |||
The amount of platelets adhering to the surface (arbitrary units × 104/mm2) derived from the image obtained by each single perfusion. Control values represent mean ± SD of 10 independent perfusions.