Table 2.

Clinical Characteristics of DLI Patients

UPN BMT To Relapse (d) Relapse to DLI (d)Status at Time of DLI T-Cell Dose (×108/kg) Acute/Chronic GVHD Response to DLI Current Clinical Status
251  361  867  HR 2.9  0/E  CR  CCR, d3484  
335  187  1,023  HR 3.4  0/E  CR  CCR, d2881  
350  1,095  63 Cy Rel  2.6  0/E  CR  CCR, d2985  
352  383 2,022  HR  1.1  I/0  NR  Alive, relapse, d3037 
357  363  230  HR  2.7  I/0  CR  Dead, GVHD 
372  376  140  HR  2.7  0/0  CR  CCR, d2546 
487  1,494  115  Cy Rel  0.1  IV/NE  CR Dead, GVHD  
506  369  65  HR  2.8  II/E  CR CCR, d2106  
563  162  67  HR  5.2  0/0  CR CCR, d1823  
593  551  71  Cy Rel  2.5  IV/NE CR* Dead, GVHD  
602  193  129  HR  2.9  0/E CR  Dead, Blast Crisis  
732  536  78  Cy Rel 0.1  0/0  CR  CCR, d1371  
755  367  45 Cy Rel  0.1  I/E  CR  CCR, d1195  
927  354 105  Cy Rel  0.1  0/NE  NE  Alive, d508 
UPN BMT To Relapse (d) Relapse to DLI (d)Status at Time of DLI T-Cell Dose (×108/kg) Acute/Chronic GVHD Response to DLI Current Clinical Status
251  361  867  HR 2.9  0/E  CR  CCR, d3484  
335  187  1,023  HR 3.4  0/E  CR  CCR, d2881  
350  1,095  63 Cy Rel  2.6  0/E  CR  CCR, d2985  
352  383 2,022  HR  1.1  I/0  NR  Alive, relapse, d3037 
357  363  230  HR  2.7  I/0  CR  Dead, GVHD 
372  376  140  HR  2.7  0/0  CR  CCR, d2546 
487  1,494  115  Cy Rel  0.1  IV/NE  CR Dead, GVHD  
506  369  65  HR  2.8  II/E  CR CCR, d2106  
563  162  67  HR  5.2  0/0  CR CCR, d1823  
593  551  71  Cy Rel  2.5  IV/NE CR* Dead, GVHD  
602  193  129  HR  2.9  0/E CR  Dead, Blast Crisis  
732  536  78  Cy Rel 0.1  0/0  CR  CCR, d1371  
755  367  45 Cy Rel  0.1  I/E  CR  CCR, d1195  
927  354 105  Cy Rel  0.1  0/NE  NE  Alive, d508 

Abbreviations: CR, complete remission; CCR, continuing complete remission; NR, no response; NE, not evaluable; HR, hematologic relapse; Cy Rel, cytogenetic relapse.

*

No morphologic evidence of leukemia in bone marrow at autopsy; no cytogenetic testing performed.

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