Table 1. FISH Analysis of... | American Society of Hematology

Table 1.

FISH Analysis of t(4;14)(p16.3;q32) in MM

Patient No.	Sex/ Age	Ig Type	Stage	PC%	Interphase^* FISH (%)	Metaphase^† FISH
1	M/67	Aλ	IA	15	8	0/6
2	M/54	Gκ	IA	20	7	0/7
3	F/66	Gκ	IA	24	11	0/20^‡
4	M/72	Gκ	IA	21	9	0/17
5	F/78	Gκ	IA	16	3	0/37
6	M/68	Gκ	IA	18	13	0/43^‡
7	M/65	Gκ	IA	13	7	0/47^‡
8	M/61	Gκ	IA	19	11	0/41
9	F/56	Gκ	IA	22	$\underset{̲}{24}$	0/37
10	F/80	Gκ	IA	28	6	0/46^‡
11	F/72	Gκ	IA	22	9	0/40
12	M/70	Gκ	IA	14	7	0/37
13	M/66	Aκ	IIA	28	$\underset{̲}{31}$	0/7
14	F/71	κ	IIA	42	12	0/43
15	M/67	Gλ	IIA	56	8	0/27
16	M/63	Gκ	IIA	39	11	0/13
17	M/36	Dκ	IIA	50	13	0/42
18	F/66	Aλ	IIA	38	$\underset{̲}{43}$	13/28
19	M/77	Gκ	IIA	52	6	0/19
20	F/64	Aκ	IIA	39	10	0/16
21	M/84	Gκ	IIA	36	8	0/23
22	M/60	Aκ	IIIA	45	12	0/37
23	M/67	Gκ	IIIB	60	10	0/27^‡
24	M/54	Aκ	IIIA	45	$\underset{̲}{41}$	0/47
25	M/76	Aλ	IIIA	49	5	0/2
26	M/79	Gκ	IIIB	56	10	0/19
27	M/57	Gκ	IIIB	46	13	0/17
28	M/66	Gκ	IIIA	54	12	0/18^‡
29	F/71	λ	IIIA	63	9	0/14
30	M/65	Aκ	PCL	86	$\underset{̲}{90}$	20/23

Patient No.	Sex/ Age	Ig Type	Stage	PC%	Interphase^* FISH (%)	Metaphase^† FISH
1	M/67	Aλ	IA	15	8	0/6
2	M/54	Gκ	IA	20	7	0/7
3	F/66	Gκ	IA	24	11	0/20^‡
4	M/72	Gκ	IA	21	9	0/17
5	F/78	Gκ	IA	16	3	0/37
6	M/68	Gκ	IA	18	13	0/43^‡
7	M/65	Gκ	IA	13	7	0/47^‡
8	M/61	Gκ	IA	19	11	0/41
9	F/56	Gκ	IA	22	$\underset{̲}{24}$	0/37
10	F/80	Gκ	IA	28	6	0/46^‡
11	F/72	Gκ	IA	22	9	0/40
12	M/70	Gκ	IA	14	7	0/37
13	M/66	Aκ	IIA	28	$\underset{̲}{31}$	0/7
14	F/71	κ	IIA	42	12	0/43
15	M/67	Gλ	IIA	56	8	0/27
16	M/63	Gκ	IIA	39	11	0/13
17	M/36	Dκ	IIA	50	13	0/42
18	F/66	Aλ	IIA	38	$\underset{̲}{43}$	13/28
19	M/77	Gκ	IIA	52	6	0/19
20	F/64	Aκ	IIA	39	10	0/16
21	M/84	Gκ	IIA	36	8	0/23
22	M/60	Aκ	IIIA	45	12	0/37
23	M/67	Gκ	IIIB	60	10	0/27^‡
24	M/54	Aκ	IIIA	45	$\underset{̲}{41}$	0/47
25	M/76	Aλ	IIIA	49	5	0/2
26	M/79	Gκ	IIIB	56	10	0/19
27	M/57	Gκ	IIIB	46	13	0/17
28	M/66	Gκ	IIIA	54	12	0/18^‡
29	F/71	λ	IIIA	63	9	0/14
30	M/65	Aκ	PCL	86	$\underset{̲}{90}$	20/23

Percentage of nuclei with colocalized signals (IGH constant and YAC746-H1 probes). Values above the 15% cutoff are underlined.

Number of metaphases with evidence of a t(4;14) out of the total number of metaphases observed in each sample.

Patients with structurally altered or an abnormal number of chromosomes 14 (see text).