Table 2.

Genes Overrepresented in Hodgkin’s Disease Versus Germinal Center B Cells

GenBank Gene NameTemplates HD:B R(g) 95% Confidence Interval
HD B
X03558 Elongation factor 1-α  252  3  794  50, 12740  
Z28407 Ribosomal protein L8  102  1  195  17, 882  
X635526  Elongation factor 1-γ  60  0  232  14, 3745  
M17885 Ribosomal phosphoprotein P0  56  2  54  13, 220  
L19739 Metallopanstimulin  30  0  117  7, 1909  
U83171 Macrophage-derived chemokine (MDC)  16  0  63  4, 1052 
L15320 Nucleophosmin B23 (NPM)  22  4  11  4, 31 
U10687 MAGE-4a  11  0  44  3, 747  
M64241 Wilm’s tumor-related (QM)  10  0  40  2, 686 
X07417 Retrotransposon SINE-R11  9  0  36  2, 625 
GenBank Gene NameTemplates HD:B R(g) 95% Confidence Interval
HD B
X03558 Elongation factor 1-α  252  3  794  50, 12740  
Z28407 Ribosomal protein L8  102  1  195  17, 882  
X635526  Elongation factor 1-γ  60  0  232  14, 3745  
M17885 Ribosomal phosphoprotein P0  56  2  54  13, 220  
L19739 Metallopanstimulin  30  0  117  7, 1909  
U83171 Macrophage-derived chemokine (MDC)  16  0  63  4, 1052 
L15320 Nucleophosmin B23 (NPM)  22  4  11  4, 31 
U10687 MAGE-4a  11  0  44  3, 747  
M64241 Wilm’s tumor-related (QM)  10  0  40  2, 686 
X07417 Retrotransposon SINE-R11  9  0  36  2, 625 

Listed are examples of genes whose adjusted relative occurrence values [R(g)] in Hodgkin’s disease (HD) were high compared with germinal center B cells (B). A complete list can be found at www.hodgkins.georgetown.edu (“Hodgkin’s cells vs. germinal center B cells”). Germinal center B cell (GCB) cDNA libraries are reported at www.ncbi.nlm.nih.gov/CGAP.

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