Table 2. Effect of ATRA on the... | American Society of Hematology

Table 2.

Effect of ATRA on the Cell-Cycle Distribution of the Parental OPM-2 and Transfected Cell Lines

Cell Lines	Treatment^*	% Cells in
Cell Lines	Treatment^*	G0/G1	S	M/G2
OPM-2	Medium	40	52	8
	ATRA, IC₉₉	58	34	7
	ATRA, IC₁₀	58	35	7
A1	Medium	59	41	<1
	ATRA, IC₉₉	79	21	<1
	ATRA, IC₁₀	80	20	<1
C4	Medium	38	50	12
	ATRA, IC₉₉	61	29	10
	ATRA, IC₁₀	59	38	3
C5	Medium	32	28	40
	ATRA, IC₉₉	83	13	5
	ATRA, IC₁₀	35	27	39

Cell Lines	Treatment^*	% Cells in
Cell Lines	Treatment^*	G0/G1	S	M/G2
OPM-2	Medium	40	52	8
	ATRA, IC₉₉	58	34	7
	ATRA, IC₁₀	58	35	7
A1	Medium	59	41	<1
	ATRA, IC₉₉	79	21	<1
	ATRA, IC₁₀	80	20	<1
C4	Medium	38	50	12
	ATRA, IC₉₉	61	29	10
	ATRA, IC₁₀	59	38	3
C5	Medium	32	28	40
	ATRA, IC₉₉	83	13	5
	ATRA, IC₁₀	35	27	39

Cells were cultured in medium with or without ATRA at 6.1 × 10⁻⁷ (IC₉₉) or at 6.8 × 10⁻⁸ mmol/L (IC₁₀) for 2 days before cytometric analysis.