Table 4.

LOH Results of Patients With MSH2 Protein Abnormalities

PatientsD2S367 D2S288 D2S391 D2S2294
 1. AH  2  LOH  LOH  
 3. BG  2  1  2  2  
 4. EH  2  1  1  
 5. EW  LOH  LOH  LOH  LOH 
 6. KP  2  1  2  1  
 7. JG  LOH  1  1  
 9. MP  2  1  1  2  
10. MRT  2  LOH 1  0  
11. MT  2  1  1  1  
13. RG  LOH  1  2  
14. SG  2  1  2  
PatientsD2S367 D2S288 D2S391 D2S2294
 1. AH  2  LOH  LOH  
 3. BG  2  1  2  2  
 4. EH  2  1  1  
 5. EW  LOH  LOH  LOH  LOH 
 6. KP  2  1  2  1  
 7. JG  LOH  1  1  
 9. MP  2  1  1  2  
10. MRT  2  LOH 1  0  
11. MT  2  1  1  1  
13. RG  LOH  1  2  
14. SG  2  1  2  

Abbreviations: 1, homozygous or uninformative; 2, constitutionally heterozygous with retention of both alleles in leukemic DNA; LOH, constitutionally heterozygous with loss of one allele in leukemic DNA; 0, constitutionally heterozygous with loss of both alleles in leukemic DNA.

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