In Vitro Differentiation of t(11;17)-Positive Leukemia Cells at First Diagnosis With ATRA and G-CSF
| . | No Culture . | Medium . | G-CSF . | ATRA . | ATRA + G-CSF . |
|---|---|---|---|---|---|
| Lymphocytes | 0.0* | 2.8 | 5.8 | 2.0 | 2.8 |
| Promyelocytes | 93.4 | 90.4 | 38.4 | 1.0 | 8.4 |
| (Meta)myelocytes | 0.4 | 1.0 | 41.8 | 84.6 | 13.6 |
| Band cells | 2.4 | 0.2 | 7.4 | 4.0 | 6.2 |
| Neutrophils | 2.2 | 5.6 | 6.6 | 8.4 | 69.2 |
| . | No Culture . | Medium . | G-CSF . | ATRA . | ATRA + G-CSF . |
|---|---|---|---|---|---|
| Lymphocytes | 0.0* | 2.8 | 5.8 | 2.0 | 2.8 |
| Promyelocytes | 93.4 | 90.4 | 38.4 | 1.0 | 8.4 |
| (Meta)myelocytes | 0.4 | 1.0 | 41.8 | 84.6 | 13.6 |
| Band cells | 2.4 | 0.2 | 7.4 | 4.0 | 6.2 |
| Neutrophils | 2.2 | 5.6 | 6.6 | 8.4 | 69.2 |
Boldface is used to emphasize the predominant phenotype of the cells.
Numbers indicate % of cells. After 1 week of culture of leukemic cells, cytospin slides were stained with May-Grünwald-Giemsa. Five hundred cells were differentiated for each slide. ATRA was used at 1 μmol/L, G-CSF at 0.1 μg/mL.