Table 3.

Immunological Recovery: Analysis of Naive (CD45RA+) and Memory (CD45RO+) T Cells Before and at Approximately One Year After Allo-BMT

Individual % CD4+ CD45RA+% CD4+ CD45RO+% CD8+ CD45RA+% CD8+ CD45RO+
Patient 1 pre-BMT  34 69  81  21  
Patient 1 post-BMT  27  71  85  14 
Patient 2 pre-BMT  60  34  66  32  
Patient 2 post-BMT  43  65  54  66  
Reference3-150 value 
 0-11 mo  81 (66-88)  
 1-6 yr  71 (66-77) 
Donor 1  60  35  82  19  
Donor 2  48  60 40  63  
Reference value  
 7-17 yr 61 (55-67) 
Individual % CD4+ CD45RA+% CD4+ CD45RO+% CD8+ CD45RA+% CD8+ CD45RO+
Patient 1 pre-BMT  34 69  81  21  
Patient 1 post-BMT  27  71  85  14 
Patient 2 pre-BMT  60  34  66  32  
Patient 2 post-BMT  43  65  54  66  
Reference3-150 value 
 0-11 mo  81 (66-88)  
 1-6 yr  71 (66-77) 
Donor 1  60  35  82  19  
Donor 2  48  60 40  63  
Reference value  
 7-17 yr 61 (55-67) 

The percentage CD45RA+ and CD45RO+ T cells was determined after staining with FITC-labeled anti-CD45RA or anti-CD45RO MoAbs and PE-labeled anti-CD4 or anti-CD8 MoAbs; CD45RA+RO+ T cells were calculated as well.

F3-150

Age-matched reference values39 are given as median with ranges from 25th to 75th percentiles in parentheses; reference values for CD8+ naive and memory T cells and for CD4+CD45RO+ T cells are not available.

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