Definition of the Measured Endpoints
| Terms . | Definition/Measured Endpoint . |
|---|---|
| Clone size Cell proliferation | Total number of nucleated cells per clone at day 10 = reflects cell proliferation |
| LTC-IC potential | Presence within a single clone of at least 1 LTC-IC at day 10 = recognized by the presence of at least 1 CFC at week 5 |
| LTC-IC recruitment | Increase in the number of clones with an LTC-IC potential at day 10 |
| LTC-IC self renewal or amplification | Presence of more than 1 LTC-IC at day 10 in individual clones |
| Terms . | Definition/Measured Endpoint . |
|---|---|
| Clone size Cell proliferation | Total number of nucleated cells per clone at day 10 = reflects cell proliferation |
| LTC-IC potential | Presence within a single clone of at least 1 LTC-IC at day 10 = recognized by the presence of at least 1 CFC at week 5 |
| LTC-IC recruitment | Increase in the number of clones with an LTC-IC potential at day 10 |
| LTC-IC self renewal or amplification | Presence of more than 1 LTC-IC at day 10 in individual clones |