Allele Frequencies and Homozygosity Rates (%) in the HLA-DRB3/4/5 Loci
| . | Newborns n = 325 . | Males n = 150 . | Females n = 175 . | Patients n = 114 . | Males n = 61 . | Females n = 53 . |
|---|---|---|---|---|---|---|
| DR51 | ||||||
| AF | 30.5 | 34.0 | 27.4 | 36.0 | 29.5 | 43.4 |
| HR | 4.3 | 6.0 | 2.9 | 2.6 | 2.3 | 3.8 |
| DR52 | ||||||
| AF | 60.1 | 67.3 | 55.4 | 44.7 | 42.6 | 47.2 |
| HR | 15.7 | 12.7 | 18.3 | 8.8 | 6.6 | 11.3 |
| DR53 | ||||||
| AF | 53.6 | 51.3 | 55.4 | 57.9 | 67.2 | 47.2 |
| HR | 8.3 | 4.0 | 12.0 | 21.1 | 32.8 | 7.5 |
| . | Newborns n = 325 . | Males n = 150 . | Females n = 175 . | Patients n = 114 . | Males n = 61 . | Females n = 53 . |
|---|---|---|---|---|---|---|
| DR51 | ||||||
| AF | 30.5 | 34.0 | 27.4 | 36.0 | 29.5 | 43.4 |
| HR | 4.3 | 6.0 | 2.9 | 2.6 | 2.3 | 3.8 |
| DR52 | ||||||
| AF | 60.1 | 67.3 | 55.4 | 44.7 | 42.6 | 47.2 |
| HR | 15.7 | 12.7 | 18.3 | 8.8 | 6.6 | 11.3 |
| DR53 | ||||||
| AF | 53.6 | 51.3 | 55.4 | 57.9 | 67.2 | 47.2 |
| HR | 8.3 | 4.0 | 12.0 | 21.1 | 32.8 | 7.5 |
Homozygosity for HLA-DR51, -DR52, -DR53 correspond to double dose of HLA-DRB5, -DRB3, -DRB4, respectively (see Materials and Methods); for P values, see Results.
Abbreviations: AF, allele frequency; HR, homozygosity rate.