Table 3.

Transduction Efficiencies of G1MD and G1Na Retroviral Vectors

Patient CD34+ Cells After G1MD Incubation ×106/kg G1MD Transduction Efficiency % CD34+ Cells After G1Na Incubation ×106/kg G1Na Transduction Efficiency % G1MDMarked CD34+ Cells Reinfused ×104/kg G1NaMarked CD34+ Cells Reinfused ×104/kg
.80  .24  .90  9  .19  8.1  
2  .57  .28 .60  25  .17  15.0  
3  .68  .33  .63  45 .22  28.4  
4  .86  .22  .71  43  .19  30.5 
5  1.08  .19  1.03  8  .21  8.2  
.66  .28  .55  52  .18  28.6  
Mean  .78 .26  .74  30.3  .19  19.8 
Patient CD34+ Cells After G1MD Incubation ×106/kg G1MD Transduction Efficiency % CD34+ Cells After G1Na Incubation ×106/kg G1Na Transduction Efficiency % G1MDMarked CD34+ Cells Reinfused ×104/kg G1NaMarked CD34+ Cells Reinfused ×104/kg
.80  .24  .90  9  .19  8.1  
2  .57  .28 .60  25  .17  15.0  
3  .68  .33  .63  45 .22  28.4  
4  .86  .22  .71  43  .19  30.5 
5  1.08  .19  1.03  8  .21  8.2  
.66  .28  .55  52  .18  28.6  
Mean  .78 .26  .74  30.3  .19  19.8 

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